IBD and the Risk of COVID-19

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To determine whether patients with IBD have an increased risk of developing SARS-CoV-2 compared with patients without IBD, a nationwide, retrospective cohort study was carried out in the U.S. Veterans Affairs Healthcare System from January 2020 to June 30, 2020. Each patient with IBD was matched with 2 patients without IBD on age, sex, race, location, and comorbidities. The outcome of interest was development of SARSCoV-2.

A total of 38,378 patients with IBD and 67,433 patients without IBD, were evaluated; 87 (0.22%) and 132 (0.20%) patients developed incident CoVID-2 infection, respectively.

It was concluded that patients with IBD are not at significantly increased risk of developing SARS CoV-2 infection when compared with patients without IBD.

Khan, N., Patel, V., Xie, D., et al. “Are Patients with Inflammatory Bowel Disease at an Increased Risk of Developing SARS/CoVID-2 than Patients Without Inflammatory Bowel Disease? Results From a Nationwide Veterans’ Affairs Cohort Study.” American Journal of Gastroenterology 2021; Vol. 116, pp. 808-810.

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