BMI, Diabetes, and Cholangiocarcinoma Risk

BMI, Diabetes, and Cholangiocarcinoma Risk

Obesity and diabetes are associated with an increased liver cancer risk. To evaluate their relationship with intrahepatic cholangiocarcinoma (ICC), the second most common cause of liver cancer, a pooled analysis was conducted with a systemic review/meta-analysis of the literature. The liver cancer pooling project was a consortium of 13 U.S. based, prospective cohort studies with data from 1,541,143 individuals (ICC cases, N = 414). In this systematic review, 14 additional studies were identified and a meta-analysis was carried out, combining the results from LCCP with the results from the 5 prospective studies identified through September 2017.