GASTROINTESTINAL MOTILITY AND FUNCTIONAL BOWEL DISORDERSForeward
GASTROINTESTINAL MOTILITY AND FUNCTIONAL BOWEL DISORDERS, SERIES #8Update In Pediatric Gastroparesis
There is a robust body of evidence for the etiology and management of adult gastroparesis, but limited in the pediatric population. Pediatric gastroparesis is usually overlooked and can remain untreated for a long period of time. The aim of this review is to provide the most up to date evidence on the spectrum of pediatric gastroparesis, emphasize the differences from the adult setting as well as extensively address management approaches and treatment recommendations.
INFLAMMATORY BOWEL DISEASE: A PRACTICAL APPROACH, SERIES #94Mucosal Healing as an Emerging Therapeutic End-Point in Inflammatory Bowel Disease
In the last few years mucosal healing (MH) has emerged as an important therapeutic goal for patients with inflammatory bowel disease. Growing evidence suggests that MC can improve patient outcomes and potentially alter the natural course of the disease. In this article, we discuss the important questions that remain to be answered. How should MH be defined? What is the impact of current treatments in healing mucosal lesions in CD and UC? What is the real impact of MH on the clinical course of IBD? In other words, is MH a valid surrogate end-point of disease outcome?
FRONTIERS IN ENDOSCOPY, SERIES #18Avoiding Misses and Near Misses: Improving Accuracy in EUS
Even expert endoscopists can miss significant lesions during an EUS examination. In this article, we discuss the challenging aspects of EUS, analyze potential causes for misses and near misses in EUS, and suggest how the endosonographer can minimize these occurrences.
NUTRITION ISSUES IN GASTROENTEROLOGY, SERIES #141Short Bowel Syndrome in Adults Part 5 Trophic Agents in the Treatment of Short Bowel Syndrome
An important goal when treating the short bowel syndrome (SBS) patient who requires parenteral nutrition or fluid support is to reduce dependency on this support and, whenever possible, to eliminate its use altogether. There is great interest in the use of growth factors in patients who have been unable to achieve enteral independence during the adaptive period despite optimization of diet and medical management. A number of pharmacological agents have been demonstrated to induce trophic properties on the intestinal epithelium. In Part V of our series on SBS, we will focus on somatropin, a recombinant human growth hormone, and teduglutide, a recombinant human glucagon-like peptide-2 analogue, the currently approved trophic factors available for use as aids to wean parenteral support in SBS.
A CASE REPORTSchistosomal Proctitis
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EXALENZ BIOSCIENCE ANNOUNCES NEW PUBLISHED DATA CONFIRMING THE CLINICAL UTILITY OF ITS BREATHID® TEST FOR DETECTING H. PYLORI IN AN EMERGENCY DEPARTMENT SETTING
Study results support a test-and-treat strategy that could benefit symptomatic patients