April 2015 Vol XXXIX Issue 4

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FRONTIERS IN ENDOSCOPY, SERIES #17

Evaluation and Therapy of Pancreatic Cysts

Serge Sorser, Ali Siddiqui, Douglas G. Adler

Multiple societal guidelines have been established to assist clinicians in directing the care of patients with pancreatic cysts, but the natural history and malignant potential of all cystic lesions is not entirely understood. In this article, we aim to describe the common types of pancreatic cysts, their natural history, means of follow up, and possible modes of endoscopic and non-endoscopic intervention.



NUTRITION ISSUES IN GASTROENTEROLOGY, SERIES #140

Short Bowel Syndrome in Adults – Part 4B A Guide to Front Line Drugs Used in the Treatment of Short Bowel Syndrome

Lingtak-Neander Chan, John K. DiBaise, Carol Rees Parrish

In patients with short bowel syndrome (SBS), malabsorption of drugs is an important consideration, particularly if the expected clinical response to a medication is not attained. Factors include length, location and health of the remaining bowel, the form of the medication administered and the site of action of the drug. Part 4B of this 5-part series will focus on conventional pharmacological agents used in the treatment of SBS.



LIVER DISORDERS, SERIES #2

An Overview of Hepatic Fibrogenesis

George Tan, Duminda Suraweera, Gaurav Singhvi

Hepatic fibrosis is a dynamic process that results from chronic liver injury. While the common mechanism involves hepatocyte injury, inflammation and eventual distortion of hepatic architecture, each etiology has a unique pathway. In this review we discuss major causes such as alcoholic liver disease, non-alcoholic fatty liver disease, chronic viral hepatitis and cholestatic liver disease. In addition we review current diagnostic modalities and provide general management principles.



INFLAMMATORY BOWEL DISEASE: A PRACTICAL APPROACH, SERIES #93

Adapting Lugasi's Core Conditions for Optimizing Transition of Pediatric to Adult Care in IBD

Joseph Kingsbery, Martin J. Wolff, Nancy McGreal, Lisa B. Malter

The incidence of pediatric-onset inflammatory bowel disease is rising. As this growing population nears adulthood, they are faced with transition of care (TOC) to adult gastroenterologists. This critical transition period has been studied in pediatric patients with chronic medical conditions and several core conditions for successful transition have been identified. In this paper we apply Lugasi’s conditions for successful transition of care specifically to patients with inflammatory bowel disease and suggest a blueprint for a successful TOC process.



GASTROINTESTINAL MOTILITY AND FUNCTIONAL BOWEL DISORDERS, SERIES #7

Pediatric Biliary Dyskinesia and Sphincter of Oddi Dysfunction

Aldo Maspons, Richard W. McCallum

Adult gastroenterologists consider biliary dyskinesia a functional disorder and new research has opened the door for Type 3 sphincter of Oddi dysfunction to be considered as a functional disorder. Pediatric gastroenterologists should follow the lead of our adult colleagues and consider the reclassification of biliary dyskinesia and sphincter of Oddi dysfunction type 3 as functional disorders.



UNUSUAL CAUSES OF ABDOMINAL PAIN, #8

Unusual Causes of Abdominal Pain

Omair Atiq, Lan Peng, Christian Mayorga



A CASE REPORT

Colonic Polypoid Ganglioneuroma

Saire Mendoza M., Parajuli D.



A CASE REPORT

Acute Liver Failure Due to Gemcitabine

William Ferges, Jeanine Chiaffarano, S. Devi Rampertab, Nakechand Pooran



Departments Section


From the Pediatric Gastroenterology Literature

Predictors of Pancreatitis Severity in Children

Pediatric acute pancreatitis (AP) is a disease process which is not well studied despite the fact that an increasing number of pediatric patients with AP are admitted to the hospital annually. The authors of this study evaluated the influence of ethnicity and nutritional status on pediatric AP severity.



What Predicts Safe Percutaneous Gastrostomy Tube Placement?

Pediatric gastroenterologists often are asked to place percutaneous endoscopic gastrostomy (PEG) tubes in children for a variety of feeding problems; however, contraindications for PEG tube placement exist, including the presence of malrotation.



Medical Bulletin Board

NEWLY REVISED RESOURCE FOR PATIENTS WITH SHORT BOWEL SYNDROME

If you work with patients who have Short Bowel Syndrome (SBS), you may want to be aware of the latest version of, A Patient's Guide to Managing a Short Bowel by Carol Rees Parrish, MS, RD. It is the first detailed patient-focused resource available on SBS.



ACUPATH LABORATORIES

Acupath Laboratories (Plainview, N.Y.) has recently announced the addition of Fluorescent in situ Hybridization (FISH) testing to further classify patients with Barrett's Esophagus. The inclusion of FISH on these types of specimens helps identify high risk Barrett's patients likely to develop esophageal adenocarcinoma, as well as differentiate lower risk patients in need of further monitoring.



BOSTON SCIENTIFIC LAUNCHES NEXT GENERATION SPYGLASSTM DS DIRECT VISUALIZATION SYSTEM FOR ADVANCED DIAGNOSIS AND TREATMENT OF PANCREATICO BILIARY DISEASES

MARLBOROUGH, MA – Boston Scientific Corporation (NYSE: BSX) announces 510(k) clearance and the first cases of the SpyGlass DS Direct Visualization System used for cholangioscopy and pancreatoscopy procedures. Built on the technology of the original SpyGlass System, the new SpyGlass DS System is designed to optimize procedural efficiency and productivity with improved ease of setup, ease of use and image quality.



EXACT SCIENCES AND MAYO CLINIC EXTEND, EXPAND COLLABORATION TO CONTINUE FIGHTING CANCER THROUGH ADVANCED SCREENING

Unique Arrangement Aims to Build on the Success of Cologuard
MADISON, WS - Exact Sciences Corp. (NASDAQ: EXAS) and Mayo Clinic announced a five-year extension and expansion of their collaboration, broadening their efforts to develop screening, surveillance and diagnostic tests beyond colorectal cancer to address other diseases within the gastrointestinal tract.



A SIMPLE PHONE CALL CAN HELP PREVENT COLON CANCER

Katie Couric and the Entertainment Industry Foundation Launch Citywide Make That Call Campaign with New York-Presbyterian and its Jay Monahan Center for Gastrointestinal Health
NEW YORK — Katie Couric, New York-Presbyterian Hospital and its Jay Monahan Center for Gastrointestinal Health, and the Entertainment Industry Foundation's National Colorectal Cancer Research Alliance want you to make that call to your doctor for colon cancer screening if you are 50 or older or otherwise at high risk for colon cancer.



Meetings Calendar

May 16-19, 2015 Digestive Disease Week
May 30-June 3, 2015 ASCRS Annual Scientific Meeting
July 18, 2015 Mastering Clinical Challenges and Emerging Therapies in IBD