A SPECIAL ARTICLEProtecting Patients' Stomachs and Hearts While Managing Their Osteoarthritis
Doctor Gitlin reviews three "GI-outcomes" studies conducted at the request of the FDA, to evaluate the risk of upper GI complications with misoprostol plus NSAIDs (the MUCOSA trial), celecoxib (the CLASS trial), or rofecoxib (the VIGOR trial). In his paper he reviews the studies, their results and application to clinical practice.
NUTRITIONAL ISSUES IN GASTROENTEROLOGY, SERIES #5Nutritional Considerations in Inflammatory Bowel Disease
Ms. Eiden writes that nutrient alterations are commonplace in patients with inflammatory bowel disease. Her paper addresses many of the nutrition issues facing clinicians such as: oral, enteral and parenteral nutrition, common vitamin and mineral deficiencies, medium chain triglycerides and nutrition as both primary and supportive therapy.
A SPECIAL ARTICLEZollinger-Ellison Syndrome Successfully Treated with Esomeprazole
In their paper doctors Sostek and Troiano describe the medical and surgical treatment of a patient who presented with diarrhea of 3-year's duration and later complained of nausea and vomiting and was found to have ZES.
FELLOWS' CORNERAppendiceal Adenocarcinoma with Peritonei
Doctor Nahar presents the case of a patient with a rare tumor and follows-up with a discussion of the case.
PEARLS OF GASTROENTEROLOGYWhen Not to Remove a Polyp
Doctors Shernoff and Siddoway write that concern for an increased risk for colon cancer prompts colonoscopy surveillance in patients who have a ureterosigmoidostomy and that the endoscopist must observe for urine output at these sites to avoid potentially disastrous "polypectomy."